Salvinorin A

Salvinorin A

Potent kappa-opioid agonist from sage family

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What is it?

Salvia divinorum contains salvinorin A - the **only known naturally occurring kappa opioid receptor agonist**. Extremely short duration (5-15 min). Intense dissociation, reality distortion. Mazatec shamanic use for divination/healing. Not suitable for recreational use. Legal in some US states.

🚨 Important Warnings

Please read all warnings carefully before use.

⚠️
HIGH

Extremely intense, disorienting. Physical safety risk (falls, injury). Always have sitter. Not recommended for most users.

⚠️
MODERATE

Sitting/lying position essential. Remove hazards. Complete loss of awareness possible. Never use in public or while standing.

🔬 Scientific Research

Current research findings and clinical studies.

Unique kappa opioid mechanism. No cross-tolerance with classic psychedelics. Dysphoric rather than euphoric for most users. Research into pain management potential.

⚖️ Legal Status

Current legal status in various jurisdictions. Always respect local laws.

Jurisdiction Status Details
US Federal
Not scheduled federally
Legal federally. Banned in many states (20+). Legal status varies widely.
Australia
Schedule 9
Prohibited substance.
Legal information may change. Always verify current legal status in your jurisdiction.

👤 Key Figures

Notable figures associated with the research and history of this substance.

👤

R. Gordon Wasson

Ethnobotanist

Documented Mazatec Salvia use with María Sabina in 1962.

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