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Curated updates on microdosing, research, policy, and community.

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2025-09-19 • Microdosing Institute

A randomised placebo-controlled study of the effects of lysergic acid diethylamide microdosing (15 μg) on pain perception in healthy volunteers

This randomised, placebo-controlled study (n=48) examining LSD microdosing (15 μg) for analgesia in healthy participants found no significant pain-relieving effects on pain tolerance or subjective pain perception usin...

Microdosing Research
2025-09-12 • Microdosing Institute

Assessing the Potential Cardiovascular Risk of Microdosing the Psychedelic LSD in Mice

This pre-clinical mouse study tested chronic administration of serotonin, d-fenfluramine, or subhallucinogenic doses of LSD on cardiovascular health. Serotonin and d-fenfluramine caused ventricular thickening and valv...

Microdosing Research
2025-08-01 • Microdosing Institute

Health-related behavioral changes following the use of psychedelics in naturalistic settings

This cross-sectional study (n=2,510) of US adults with psychedelic experience found that participants retrospectively reported widespread improvements in health behaviours including reduced alcohol (66%) and tobacco (...

Microdosing Research
2025-07-20 • Microdosing Institute

Safety and tolerability of multiple sublingual microdoses of 5-MeO-DMT in adults with moderate symptoms of depression and/or anxiety: a randomized, double-blind, placebo-controlled study

This Phase I clinical trial (n=36) of sublingual 5-MeO-DMT (6-12 mg weekly doses over four weeks) in adults with moderate to high anxiety/depression demonstrated good safety and tolerability with no significant advers...

Microdosing Research
2021-09-17 • Psychedelic Times

Visionary Art and Psychedelics: Interview with Amanda Sage

The following is a guest post by visionary artist Veronika Rose. Amanda Sage is a world-famous visionary artist currently based out of Gunnison, Colorado. Known for her luminous, colorful, and […] The post Visionary A...

Microdosing
2021-07-05 • EntheoNation

Microdosing DMT… Wait, That’s a Thing?

As more and more folks seek healing in the practice of taking small amounts of psilocybin or LSD a few times per week, some more adventurous wellness explorers have been experimenting with microdosing DMT. What does t...

Microdosing
2021-06-01 • EntheoNation

Microdosing Huachuma Cactus vs. Magic Mushrooms

Huachuma cactus and magic mushrooms are two popular plant medicines to microdose with. Which is the better choice for you? The post Microdosing Huachuma Cactus vs. Magic Mushrooms appeared first on EntheoNation.

Microdosing
2021-06-01 • EntheoNation

Microdosing Huachuma: Sacred Cactus of the Andes

Huachuma, or San Pedro, is a sacred cactus containing the psychedelic molecule mescaline. Can you microdose it? We cover the basics here. The post Microdosing Huachuma: Sacred Cactus of the Andes appeared first on Ent...

Microdosing