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Psychedelics News
Curated updates on microdosing, research, policy, and community.
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Language-associated brain representations covary with disruption of selfhood under psilocybin
This fMRI preprint analysed psilocybin (19 mg) in healthy adults (n=43 for ego dissolution; n=50 in the shared imaging pool). Stronger ego dissolution was associated with greater representational similarity in a langu...
Participant experiences and recommendations for psychedelic clinical trials and future treatment delivery: a qualitative study with experts by experience from the Psychedelic Participant Advocacy Net…
This qualitative study (n=4) explored former psychedelic-trial participants’ experiences of recruitment, preparation, dosing, integration and study ending. Participants said communication, staff relationships, uncerta...
Cumulus Neuroscience and Transpharmation have partnered to align EEG and behavioural measures from preclinical CNS research through first-in-human studies.
The companies will work with biopharma sponsors to carry quantitative EEG and behavioural endpoints from animal models into clinical and home monitoring through Cumulus’s NeuLogiq platform. A February 2026 cross-speci...
Participant experiences and recommendations for psychedelic clinical trials and future treatment delivery: a qualitative study with experts by experience from the Psychedelic Participant Advocacy Net…
This qualitative study (n=4) explored former psychedelic-trial participants’ experiences of recruitment, preparation, dosing, integration and study ending. Participants said communication, staff relationships, uncerta...
Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin (NCT07721467, psilocybin)
This Phase II, randomised, open-label, parallel-group trial (n=200) will assess whether psilocybin can enhance the neuroplastic and cognitive effects of cognitive training in older adults with early-stage Alzheimer’s ...
Rhelion Life Sciences has reappointed Dr Robin Carhart-Harris as scientific advisor to support its research programmes and collaborations through its Filament Health subsidiary.
Carhart-Harris will provide scientific and strategic input, meet regularly with management and introduce researchers, clinicians and academic institutions. Filament develops and supplies PEX010, a standardised, GMP-ma...
The DEA proposed a new temporary order to keep MGM-15 and MGM-16, two 7-hydroxymitragynine-related substances, in Schedule I under the Controlled Substances Act.
The Drug Enforcement Administration proposed a temporary order covering MGM-15 and MGM-16, including their possible isomers, esters, ethers and salts. The order would maintain their temporary Schedule I placement foll...
Language-associated brain representations covary with disruption of selfhood under psilocybin
This fMRI preprint analysed psilocybin (19 mg) in healthy adults (n=43 for ego dissolution; n=50 in the shared imaging pool). Stronger ego dissolution was associated with greater representational similarity in a langu...
Ketamine relieves pain without 'disconnecting' consciousness, study finds
An imaging study in humans led by Tel Aviv University's Institute for Psychedelic Research, in collaboration with TAU-affiliated Tel Aviv Medical Center (Ichilov), found that the pain relief provided by ketamine does ...
Definium Therapeutics Announces New Employee Inducement Grants
NEW YORK, October 13, 2026--Definium Therapeutics, Inc. ("Definium" or the "Company"), a late-stage clinical biopharmaceutical company developing a new generation of therapeutics intended to address…
Ketamine and psychedelics share a surprising link to the immune system
Ketamine and psychedelics relieve severe depression in hours, but their exact mechanisms remain elusive. New research suggests these rapid-acting drugs share a biological pathway, fighting depression by rebalancing sp...
Global Psychedelic Summit 2026
I was incredibly lucky to have been invited to attend the Global Psychedelic Society Summit in Portugal, which ran from the 23rd to the 27th of September. There I met with other psychedelic society leaders from all ar...
Neurite Complexity and Plasticity Markers Track Synaptic Vesicle Density in the Living Human Brain: A Multimodal PET-MRI-EEG Study
This multimodal brain imaging study (n=18) of healthy volunteers used PET, MRI and EEG to examine how synaptic vesicle density relates to brain structure and plasticity after ketamine (n=11) or DMT (n=7). Synaptic den...
Neurite Complexity and Plasticity Markers Track Synaptic Vesicle Density in the Living Human Brain: A Multimodal PET-MRI-EEG Study
This multimodal brain imaging study (n=18) of healthy volunteers used PET, MRI and EEG to examine how synaptic vesicle density relates to brain structure and plasticity after ketamine (n=11) or DMT (n=7). Synaptic den...
Weekly Psychedelic Policy Briefing: October 12, 2026
FDA laid out how the first federally funded ibogaine trials could be run, with inpatient cardiac monitoring and a 10 mg/kg starting dose ceiling. Compass Pathways executives discussed pricing as the COMP360 NDA nears ...