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Gut Feeling: Links Between LSD, Endocannabinoids, and the Microbiome
In the last 10 years, psychiatric interest in the use of psychedelics, such as psilocybin and LSD, has surged. A new study employed mice to examine how LSD could exert changes on the inflammatory response and the gut ...
Abuse Potential: Considerations for Rescheduling MDMA and Psychedelics
Can the meteoric rise of psychedelics and entactogens clear the legal hurdles of abuse potential assessment and rescheduling?
Many Trips, Diminishing Returns: Cross-Tolerance Between LSD and DOI
Psychedelic drugs like LSD powerfully alter consciousness and promote neural plasticity, but drug tolerance occurs rapidly following the first dose. Although the mechanisms that underlie psychedelic tolerance may over...
How To Stop A Psychedelic Trip: The Promise of Ketanserin
Psychedelic trips often unfold without issues, but what if a trip needs to be stopped? Drugs such as benzodiazepines and antipsychotics are recommended as rescue medications and have been around for decades. Can ketan...
Psychedelic Brains In A Dish
Lab grown brains help to shed insight on 5-MeO-DMT mechanisms.