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Psychedelics News
Curated updates on microdosing, research, policy, and community.
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The Best Psychedelic Education Does Not Look Psychedelic
Devon Phillips, partnerships manager at MAPS, argues that people rarely change because they got better information. They change when it arrives through someone they already trust. A case for meeting curiosity where it...
Psilocybin-Assisted Therapy for Intergenerational Trauma (NCT06899165, psilocybin)
This open-label Phase II trial (n=100) will study the safety, tolerability, and potential therapeutic effects of psilocybin (2 x 25 mg oral doses, taken at least 3 weeks apart) in the biological children of genocide s...
Biphasic Hierarchical Reorganization and Riemannian Connectomic Plasticity: A Longitudinal Precision Functional Mapping Study of Psilocybin
This brain imaging study (n=7) used 101 sessions of precision functional mapping to track how psilocybin reshapes brain network organisation over time, finding a sharp acute collapse of the hierarchy separating sensor...
The Trimbos Institute issued a Red Alert after Trump-shaped ecstasy pills containing high concentrations of PMMA were submitted to Dutch drug-testing centres.
The institute warned that PMMA takes longer to act than MDMA, increasing the risk that users take more and suffer an overdose or potentially fatal overheating. No confirmed cases of PMMA in users’ blood were reported,...
Biphasic Hierarchical Reorganization and Riemannian Connectomic Plasticity: A Longitudinal Precision Functional Mapping Study of Psilocybin
This brain imaging study (n=7) used 101 sessions of precision functional mapping to track how psilocybin reshapes brain network organisation over time, finding a sharp acute collapse of the hierarchy separating sensor...
Why Most Drugs Fail, and Why Virtual Tissue Models Beat Virtual Cell Models
Welcome back to Business Trip by PsyMed Ventures, a podcast exploring the future of mental health & wellness!
Ibogaine’s Momentum Is Real. So Is the Safety Gap Nobody’s Solving.
Recent reporting, has documented a string of serious adverse events at overseas psychedelic clinics such as cardiac deaths, treatment-related fatalities, and patients who were never adequately screened for the health ...
Study shows sharp increase in rate of unintentional ingestions of recreational drugs among young children since 2000
A new study reveals that unintentional ingestions of recreational drugs by young children have increased dramatically in the past 25 years. Researchers at the Center for Injury Research and Policy of the Abigail Wexne...
The hallucinogenic plant Salvia divinorum relieves facial pain, study finds
A compound extracted from a hallucinogenic mint plant used in traditional Mexican medicine reduces facial nerve pain in mice. The findings reveal the biological mechanism behind the plant’s historic use and highlight ...
Longitudinal changes in depressive symptoms following naturalistic ayahuasca use: A prospective cohort study in Las Vegas, Nevada
This prospective observational cohort study (n=87) followed adults after naturalistic ayahuasca use in the United States and found that average depressive symptom scores were lower from 48 hours to 90 days afterwards....
Psilera appointed Allyson Gage, PhD, as Vice President of Clinical Development to lead the Phase 1a first-in-human trial of its neuroplastogen PSIL-006.
Gage will oversee the trial, which will assess PSIL-006’s safety, tolerability and biomarkers in support of development for depression, addiction, PTSD and neurodegeneration. Psilera said the programme follows an $8.8...
A dominant frontoparietal beta oscillatory brain state in the days after psilocybin and 5-MeO-DMT
This observational EEG study (n=42) found that people who had used psilocybin/LSD or 5-MeO-DMT within the previous three weeks showed a dominant right frontoparietal beta-wave brain state, linked to the time since use...
Pilot study comparing the effects of high dose THC to high dose psilocybin and placebo in the set and setting of a classic psychedelic therapy session
This double-blind, placebo-controlled crossover pilot study (n=4) compared oral Δ9-THC (25 or 50 mg) with psilocybin (25 mg) and placebo in healthy adults during a psychedelic therapy-style session. A 25 mg dose of Δ9...
Longitudinal changes in depressive symptoms following naturalistic ayahuasca use: A prospective cohort study in Las Vegas, Nevada
This prospective observational cohort study (n=87) followed adults after naturalistic ayahuasca use in the United States and found that average depressive symptom scores were lower from 48 hours to 90 days afterwards....
Ceruvia Lifesciences received three U.S. patent allowances and a European Unitary Patent grant covering BOL-148, a non-hallucinogenic LSD analogue being developed for cluster headache.
The U.S. allowances cover BOL-148’s proprietary crystalline form, 2-Br-LSD HBr, and two high-purity manufacturing processes, including routes starting from bromocriptine. Ceruvia also obtained a European Unitary Paten...