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Psychological change processes in alcohol use disorder: A qualitative study of 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) with cognitive behavioural therapy

2026-08-03 β€’ Blossom Pulse: Papers

Article summary

This qualitative study (n=10 participants, six therapists) explored psychological changes after a single intranasal dose of 5-MeO-DMT alongside psychological support and cognitive behavioural therapy for alcohol use disorder. Participants and therapists described improved self-awareness, emotional openness, flexibility and relationships, with some participants reporting abstinence or reduced compulsive drinking at 12 weeks.

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