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No evidence for deleterious effects of psilocybin and MDMA on working memory or related neurophysiological activity in a non-clinical population: An uncontrolled exploratory study

2026-07-23 β€’ Blossom Pulse: Papers

Article summary

This uncontrolled exploratory study (n=29 per drug) examined working memory and related brain activity before and after a single dose of psilocybin or MDMA in healthy participants. It found no evidence of lasting working memory harm, and both drugs were linked to changes in brain activity, with improved task accuracy after MDMA and at three-month follow-up in both groups.

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