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Mystical but not challenging experiences predict symptom improvement after psilocybin for treatment-resistant OCD

2026-09-08 β€’ Blossom Pulse: Papers

Article summary

This exploratory secondary analysis (n=27) found that stronger mystical experiences during psilocybin sessions were associated with lower OCD symptom severity one and 12 weeks later. Challenging experiences did not predict improvement, and the associations persisted after adjustment for baseline severity and treatment condition.

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