Language-associated brain representations covary with disruption of selfhood under psilocybin

This fMRI preprint analysed psilocybin (19 mg) in healthy adults (n=43 for ego dissolution; n=50 in the shared imaging pool). Stronger ego dissolution was associated with greater representational similarity in a language-associated network and altered visual, thalamic and frontal connectivity; the correlational findings do not establish a causal role for language.