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Ketamine-enhanced psychotherapy for smoking cessation: A pilot study of feasibility, safety, and clinical outcomes

2026-09-25 β€’ Blossom Pulse

Article summary

This open-label pilot study (n=7) assessed three weekly intramuscular ketamine sessions (50 mg/70 kg) combined with motivational enhancement therapy for smoking cessation. All participants completed treatment, which was well tolerated apart from expected temporary psychoactive effects, and smoking and craving decreased while withdrawal, nicotine dependence and motivation to quit remained unchanged.

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