Citizens Commission on Human Rights International urged the FDA not to approve psychedelic drugs for mental disorders or emotional distress, citing risks including aggression and psychosis.

Citizens Commission on Human Rights International submitted comments opposing approval of psilocybin, LSD, DMT, mescaline and other psychedelics for mental disorders or emotional distress. It called for strict limits on consent, administration and accountability, and highlighted safety concerns including acute psychosis and difficulties blinding trials because of noticeable drug effects.