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Circulating MicroRNAs and Their Associations with Neurotrophic, Inflammatory and Glutamate Markers in Healthy Volunteers

2026-08-10 β€’ Blossom Pulse: Papers

Article summary

This secondary analysis of an RCT (n=62) examined whether changes in small molecules in the blood could reflect how the body and brain respond to psilocybin. Psilocybin temporarily altered two microRNAs (molecules that regulate gene activity), and these changes were linked to psilocybin exposure and brain chemistry, but not to markers of inflammation. The findings suggest that blood microRNAs could potentially help measure individual biological responses to psychedelics.

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