A UCSF study found lower inflammatory markers in 12 people with Parkinson’s disease after two psilocybin sessions, with changes lasting about a month.

Researchers measured blood inflammatory markers and a mitochondrial stress marker in 12 people with Parkinson’s disease before and after two psilocybin sessions. Inflammatory markers were lower for about a month, while mitochondrial stress markers improved shortly after dosing but not over the longer term, offering early human evidence of possible inflammation modulation.